LOW T-CELL PROPORTION IN THE TUMOR MICROENVIRONMENT IS ASSOCIATED WITH IMMUNE ESCAPE AND POOR SURVIVAL IN DIFFUSE LARGE B-CELL LYMPHOMA

Low T-cell proportion in the tumor microenvironment is associated with immune escape and poor survival in diffuse large B-cell lymphoma

The tumor microenvironment (TME) is important in Insulated Beverage Server Lids the pathogenesis and prognosis of lymphoma.Previous studies have demonstrated that features of the diffuse large B-cell lymphoma (DLBCL) TME can be associated with prognosis, but questions remain about the mechanisms underlying these TME features, and the interplay betw

read more

Histone modification profiling in breast cancer cell lines highlights commonalities and differences among subtypes

Abstract Background Epigenetic regulators are frequently mutated or aberrantly expressed in a variety of cancers, leading to altered transcription states that result in changes in cell identity, behavior, Toys and response to therapy.Results To define alterations in epigenetic landscapes in breast cancers, we profiled the distributions of 8 key his

read more


Endocrine Disruption of the Follicle-Stimulating Hormone Receptor Signaling During the Human Antral Follicle Growth

An increasing number of pollutants with endocrine disrupting potential are accumulating in the environment, increasing the exposure risk for humans.Several of them are known or suspected to interfere with endocrine signals, impairing reproductive functions.Follicle-stimulating hormone (FSH) is a glycoprotein playing an essential role in supporting

read more

Genome-wide analysis of the Dof transcription factor gene family reveals soybean-specific duplicable and functional characteristics.

The Dof domain Notebooks protein family is a classic plant-specific zinc-finger transcription factor family involved in a variety of biological processes.There is great diversity in the number of Dof genes in different plants.However, there are only very limited reports on the characterization of Dof transcription factors in soybean (Glycine max).I

read more